The Hidden Crisis: Why Women Are Widely Misdiagnosed for Sleep Apnea

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For generations, the image of obstructive sleep apnea (OSA) has been firmly entrenched in the public consciousness: an older, heavy-set man loudly snoring on a couch, gasping for breath in the middle of the night. This enduring stereotype has shaped not only how the public views the condition, but unfortunately, how the medical community approaches diagnosis and treatment. However, health experts emphasize that obstructive sleep apnea is far from a "male disease." Millions of women grapple with the disorder every day, often enduring years of fatigue, headaches, and anxiety while their true underlying health issue remains entirely undetected.

Women frequently experience a wide array of vague, disruptive symptoms that compromise their daily lives, no matter how restorative their sleep habits appear to be. From persistent morning headaches and daytime jitters to profound exhaustion that makes it difficult to keep their eyes open at work, these challenges are often brushed off as simple consequences of menstruation, menopause, the demands of motherhood, or general stress. Yet beneath these everyday complaints lies a medical condition that has historically been studied, defined, and diagnosed almost exclusively through the lens of male biology.

It was not until the 1990s that researchers first recognized that obstructive sleep apnea—a disorder defined by repeated interruptions in breathing during sleep—frequently presents differently in women than it does in men. For starters, women with the condition may not even snore. Despite growing awareness, there remains much to discover about the biological mechanisms underlying these distinctions. Current research suggests that hormonal fluctuations throughout a woman’s life, anatomical differences in the upper airway, and even social stigmas regarding how women are expected to sleep all play significant roles in masking the condition.

The disease itself was defined in men, explains Jennifer Martin, PhD, a behavioral sleep medicine specialist and professor at Florida International University’s Herbert Wertheim College of Medicine in Miami. The way men and women breathe when they are asleep is not the same, and the traditional medical definition of the disease simply does not account for those physiological differences.

Although obstructive sleep apnea appears to be less common and typically milder in women before menopause, studies suggest that the long-term consequences of the disease, if left untreated, can be just as severe—if not worse—than in men. This makes recognizing the signs and seeking appropriate medical intervention critical.

How and why sleep apnea differs in women

Sleep apnea is part of a broader category known as sleep-disordered breathing. The most prevalent form is obstructive sleep apnea, which occurs when the upper airway repeatedly collapses during slumber, restricting the flow of air to the lungs, explains Anita Valanju Shelgikar, MD, a sleep medicine physician with University of Michigan Health and president of the American Academy of Sleep Medicine.

The textbook symptoms of this condition—determined largely through historical studies heavily skewed toward male participants—include loud snoring and dramatic, sudden gasps for air. However, Dr. Shelgikar notes that this profile rarely matches the reality for female patients. Instead, women with OSA are significantly more likely to experience nightmares, frequent nighttime awakenings, difficulty staying asleep, and chronic insomnia. These disruptions subsequently manifest as daytime fatigue, morning headaches, and noticeable mood swings. Furthermore, women tend to experience more hypopneas, which are characterized by shallow breaths and reduced oxygen flow, whereas men are more prone to apneas, representing complete pauses in breathing.

Some experts speculate that snoring may be underreported among women due to social embarrassment, given that societal expectations often pressure women to maintain a serene, quiet demeanor even while sleeping. However, a rapidly expanding body of research points to biological factors as a much stronger explanation for these sex-based differences. Compared with men, women generally possess smaller, structurally more stable airways that are less prone to the severe collapse and subsequent vibration that causes loud snoring. Women also tend to store less fat around their necks. Before menopause, they benefit from the protective physiological effects of estrogen and progesterone, hormones that actively interact with the respiratory system to support stable breathing patterns.

These protective factors help explain why more men than women in the United States suffer from the condition, accounting for approximately 59% and 41% of obstructive sleep apnea patients, respectively. However, once women transition through menopause and their estrogen and progesterone levels decline, the incidence and severity of OSA increase dramatically. Studies indicate that between 47% and 67% of postmenopausal women suffer from obstructive sleep apnea, a prevalence rate comparable to men in the same age group of 50 and older. The staggering gap lies in how many of these women actually receive a proper diagnosis.

Regardless of age, women continue to report a higher burden of sleep apnea-related symptoms than men, even when presenting with a milder form of the condition. Dr. Martin notes that this is likely because women experience more subtle, frequent breathing disturbances throughout the night that quietly erode the overall restorative quality of their rest.

Why misdiagnoses are common in women with sleep apnea

Because women frequently fail to display classic OSA symptoms, they are routinely misdiagnosed or dismissed by healthcare providers. When a male patient visits a physician complaining of daytime sleepiness and loud snoring, he is typically fast-tracked for a diagnostic sleep study. In contrast, when a woman reports poor sleep and heavy fatigue, she is rarely referred for similar screening. In fact, existing research suggests that men are nine times more likely to be referred for diagnostic testing than women.

Women with OSA frequently find their symptoms attributed to conditions like depression, anxiety, insomnia, or normal menopausal transitions, or even written off as medication side effects, according to Dr. Shelgikar, who also serves as a neurology professor at the University of Michigan Medical School. Compounding the issue, women can suffer from these concurrent conditions simultaneously, making sleep apnea far harder to detect while actively worsening its severity. Consider the double burden of insomnia and OSA: having both disorders at the same time is more prevalent among women. In many cases, these patients may be prescribed sleep aids, such as antihistamines or benzodiazepines, which can further relax throat muscles, exacerbate airway collapse, and leave the patient even more deprived of oxygen.

The diagnostic criteria themselves remain fundamentally male-centric. When clinicians diagnose sleep apnea, they generally require breathing interruptions to be accompanied by a precipitous drop in oxygen levels or a brief, measurable awakening from sleep. Because women do not typically experience the same steep oxygen drops as men, the established definition of the disease inherently biases diagnostic tools toward male presentations. Furthermore, Medicare—the health insurance program relied upon by the vast majority of Americans aged 65 and older—traditionally recognizes a sleep apnea diagnosis only when a patient demonstrates those steep drops in oxygen saturation, meaning typical mid-slumber wake-ups often go uncounted.

At-home sleep apnea tests, increasingly utilized as a more affordable and convenient alternative to gold-standard in-lab polysomnography, are similarly prone to missing the condition in women. Because women tend to have fewer and less pronounced events during the night, home monitors may struggle to capture the full picture. The margin of error widens further for women suffering from insomnia, who may simply not sleep enough during a home monitoring session to yield an accurate reading, leading the device to underestimate the true severity of their condition.

Experts emphasize that sleep apnea is likely far more widespread among women than current health data indicates. This reality highlights a sobering truth: countless women living with the condition are failing to receive the specialized care they desperately need, allowing a delayed diagnosis to snowball into a cascade of preventable health complications.

Why you should treat your sleep apnea

Leaving obstructive sleep apnea untreated can trigger severe downstream effects throughout the body, particularly on the cardiovascular system, notes Atul Malhotra, MD, research chief of pulmonary, critical care, and sleep medicine at UC San Diego Health. Every time breathing stops, the body perceives the sudden oxygen deficit as a crisis, releasing the stress hormone adrenaline to jolt the person awake just enough to take a breath. This process happens rapidly—often lasting only a few seconds—leaving the individual with no conscious memory of the awakening the following morning.

Over time, this relentless nocturnal stress places immense strain on the cardiovascular system, increasing the long-term risk of high blood pressure, heart attack, stroke, irregular heart rhythms, and heart failure. While empirical evidence remains mixed, some studies suggest that women with severe sleep apnea may be particularly vulnerable to cardiovascular complications compared to men. Research also shows that women often present with a higher accumulation of concurrent health conditions upon an OSA diagnosis, including thyroid disease, asthma, and depression. Whether sleep apnea precipitates these conditions or merely coexists with them, treating OSA remains a vital step in improving overall health.

Because obstructive sleep apnea severely degrades the quality of restorative rest, it is also closely linked to memory and cognitive lapses, as well as poor daytime alertness. These deficits can elevate the risk of accidents at work or on the road, particularly in high-risk professions involving transportation and construction. Less frequently discussed is the profound toll untreated sleep apnea takes on emotional well-being and personal relationships. Experts note that sleep disorders are rarely considered as potential root causes of mental health symptoms, yet managing OSA has been shown to significantly alleviate symptoms of anxiety and depression in affected individuals.

As medical researchers continue working to refine diagnostic frameworks and deepen their understanding of sex-based differences in sleep medicine, specialists emphasize a clear path forward. Strong clinical evidence demonstrates that women benefit at least as much as men—if not more—from proper sleep apnea treatment, underscoring the urgent necessity of identifying the condition early and advocating for comprehensive care.

Layla Zulfa

Layla Zulfa

Content editor and sustainable journalism contributor at GenerateGreen.